The administration is done inside the muscle mass. The vaccines containing adjuvants should be injected intramuscular to reduce the adverse effects of vaccination. It is suggested to use needles with long length for intramuscular route of administration, which cause less redness and swelling at the time of administration. The length of needles depends on the age and body mass. The techniques play an important parameter to ensure safe and efficient vaccine delivery. The intramuscular injection is administered at an angle of XX degrees to the skin and preferably into the deltoid muscle of the upper arm or the anterolateral aspect of the thigh. Moreover, depending upon the age of the patient the route of administration is decided.
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The first human vaccine against viruses were developed using attenuated or weaker viruses to generate immunity. Vaccines are developed using different processes which may include, live viruses, inactivated (killed), inactivated toxins, and segments of the pathogens. The rabies vaccine was the first human vaccine developed with attenuated live virus in the laboratory. Vaccines play major role in the public health. Vaccine provides protection to an individual from developing an infectious disease. The major challenge in the vaccine development is the illness caused to an individual through vaccination.
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Thus, to overcome this challenge researcher has designed different types of vaccines.
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